Home/ISLA Protocol™

Integrated Symptom and Lab Assessment for maternal mental health

The ISLA Protocol™

A free clinical education tool that maps twelve nutrient biomarkers to mood before and after birth, then gives you a plain-English report to discuss with your provider.

12biomarkers
2tracks, prenatal and postpartum
$0to use, no account
Maryann Walsh in a white lab coat
Created by Maryann Walsh, RD
MoodRoot™ report · examplePostpartum track
Copper : Zinc ratioFlagged
Omega-3 indexFlagged
FerritinSuboptimal
25-OH Vitamin DOptimal
Example reportNot a diagnosis

Why it exists

Built by a dietitian who lived it.

One in five mothers experiences a perinatal mood or anxiety disorder, and most are never screened for nutritional contributors.

Maryann has written openly about her own perinatal mental health crisis after becoming a mother. She created the ISLA Protocol, named for her daughter, so that other mothers and their providers would have the nutrition side of the picture in front of them.

Read her story: “I Was One of the Lucky Ones” →

A complement, not a replacement.ISLA is not a diagnostic tool and does not replace medical, nutritional or mental health care. Medication and therapy are often the most appropriate interventions. The tool is not yet validated in a clinical trial.

1 in 5

mothers experiences a perinatal mood or anxiety disorder. ISLA puts the nutrition questions on the table alongside every other kind of care.

Perinatal mood and anxiety disorders

How it works

Ten questions, your labs, one report.

Two tracks. Prenatal reads labs as risk stratification; postpartum reads them as a root-cause investigation for people who recently delivered or have current mood symptoms.

Pre-screen3 / 10

How has your energy been over the past two weeks?

01

Symptom pre-screen

Ten questions on mood, energy, sleep, anxiety and cognition.

Your labsExample
Ferritin38 ng/mL
25-OH Vitamin D41 ng/mL
RBC Magnesium5.
Serum B12 
02

Lab value entry

Enter values directly, no account required. Scoring uses functional ranges rather than standard lab ranges.

MoodRoot™ reportExample
Copper : Zinc
Omega-3 index
Ferritin
Homocysteine
Vitamin D
03

MoodRoot™ report

A color-coded report with what each flag might mean and what to discuss with your provider. Print or save as PDF.

The panel

Twelve markers, in one draw.

Some markers need specific specimen types, such as RBC magnesium and RBC folate. The free printable panel list shows each one for your provider.

12markers · one draw
MineralsIron, B vitamins and methylationOmega-3 and vitamin DThyroid

Minerals

4 markers
  • 01Copper : Zinc ratio
  • 02Ceruloplasmin
  • 03Serum Zinc
  • 04RBC MagnesiumRBC specimen

Iron, B vitamins and methylation

4 markers
  • 05Ferritin
  • 06Serum B12
  • 07RBC FolateRBC specimen
  • 08Homocysteine

Omega-3 and vitamin D

2 markers
  • 09Omega-3 indexEPA + DHA
  • 1025-OH Vitamin D

Thyroid

2 markers
  • 11TSH
  • 12Free T4
The tool

Free to use

No account required. Answer the pre-screen, enter your values and read your report.

Panel list

Bring it to your provider

A free printable list of every marker. Insurance may cover tests a provider orders.

Complete lab panel

$275

One draw, all twelve

Through Fullscript, one Quest Diagnostics draw, results in 3 to 5 business days, FSA and HSA eligible.

For clinicians

Bring ISLA into your practice.

OBs, midwives, psychiatric providers and therapists can use the panel list and report as a shared starting point with patients. Maryann answers clinician questions personally.

Ask about clinical use

If you are struggling right now

  • Postpartum Support International: 1-800-944-4773 (English), 971-203-7773 (Español)
  • National Maternal Mental Health Hotline: 1-833-852-6262, free and confidential, 24/7
  • 988 Suicide and Crisis Lifeline: call or text 988, 24/7
  • Crisis Text Line: text HOME to 741741
  • In an emergency, call 911